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The anti-inflammatory cytokine interleukin-10 (IL-10) has been explored previously as a treatment method for spinal cord injury (SCI) due to its ability to attenuate pro-inflammatory cytokines and reduce apoptosis. Primary limitations when using systemic injections of IL-10 are that it is rapidly cleared from the injury site and that it does not cross the blood-spinal cord barrier.
Pubmed ID: 31039819 RIS Download
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THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5,2022.Tool that predicts interactions between transcription factors and their regulated genes from binding motifs. Understanding vertebrate development requires unraveling the cis-regulatory architecture of gene regulation. PRISM provides accurate genome-wide computational predictions of transcription factor binding sites for the human and mouse genomes, and integrates the predictions with GREAT to provide functional biological context. Together, accurate computational binding site prediction and GREAT produce for each transcription factor: 1. putative binding sites, 2. putative target genes, 3. putative biological roles of the transcription factor, and 4. putative cis-regulatory elements through which the factor regulates each target in each functional role.
View all literature mentionsThis unknown targets The initial immunization was performed with a preparation of full length human recombinant GFAP expressed in bacteria and highly purified
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View all literature mentionsThis monoclonal targets MOUSE ANTI RAT CD45:RPE-Alexa Fluor 750
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View all literature mentionsThis monoclonal targets Cd163
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View all literature mentionsThis polyclonal targets
View all literature mentionsThis unknown targets Rabbit IgG (H+L)
View all literature mentionsThis unknown targets The initial immunization was performed with a preparation of full length human recombinant GFAP expressed in bacteria and highly purified
View all literature mentionsThis polyclonal targets MARCO antibody
View all literature mentionsThis unknown targets
View all literature mentionsThis monoclonal targets MOUSE ANTI RAT CD163
View all literature mentionsThis polyclonal secondary targets Mouse IgG (H+L)
View all literature mentionsThis monoclonal targets MOUSE ANTI RAT CD45:RPE-Alexa Fluor 750
View all literature mentionsThis monoclonal targets Rat CD86
View all literature mentionsThis monoclonal targets Rat CD68
View all literature mentionsThis unknown targets
View all literature mentionsThis monoclonal targets Rat CD11b
View all literature mentionsThis monoclonal targets Cd163
View all literature mentionsThis unknown targets Rabbit IgG (H+L)
View all literature mentionsThis unknown targets
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