Inflammasome-mediated pyroptosis is an important neuronal cell death mechanism. Previous studies reported that activation of melanocortin MC4 receptor exerted neuroprotection in several neurological diseases. Here, we have investigated the role of MC4 receptor activation with RO27-3225 in suppressing neuronal pyroptosis after experimental intracerebral haemorrhage (ICH) and the underlying mechanism.
Pubmed ID: 30811584 RIS Download
Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.
This monoclonal targets NeuN
View all literature mentionsThis polyclonal targets IL1 beta
View all literature mentionsThis polyclonal targets ACTG1, ACTC1, ACTA1, ACTA2, ACTG2, ACTB
View all literature mentionsThis unknown targets Caspase 1
View all literature mentionsThis monoclonal targets JNK1+JNK2+JNK3
View all literature mentionsThis monoclonal targets p-p38 (D-8)
View all literature mentionsThis monoclonal targets JNK1 + JNK2 + JNK3(phospho T183+T183+T221) (phospho T183 + T183 + T221) antibody [EPR5693]
View all literature mentionsThis monoclonal targets MAPK14, MAPK11
View all literature mentionsThis unknown targets ASK1, phospho (Ser967)
View all literature mentionsThis polyclonal targets MC4R
View all literature mentionsThis monoclonal targets ASK1 (D11C9) Rabbit mAb
View all literature mentionsMicroscope software platform which integrates Leica automated microscopes and digital cameras and provides one common user interface.
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsMus musculus with name Crl:CD1(ICR) from IMSR.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsMicroscope software platform which integrates Leica automated microscopes and digital cameras and provides one common user interface.
View all literature mentionsOpen source Java based image processing software program designed for scientific multidimensional images. ImageJ has been transformed to ImageJ2 application to improve data engine to be sufficient to analyze modern datasets.
View all literature mentionsThis polyclonal targets MC4R
View all literature mentionsMus musculus with name Crl:CD1(ICR) from IMSR.
View all literature mentions