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A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network.

EBioMedicine | 2018

Activation of intrinsic p53 tumor-suppressor (TS) pathways is an important principle underlying cancer chemotherapy. It is necessary to elucidate the precise regulatory mechanisms of these networks to create new treatment strategies.

Pubmed ID: 30049386 RIS Download

Research resources used in this publication

Antibodies used in this publication

Associated grants

None

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.


DAVID (tool)

RRID:SCR_001881

Bioinformatics resource system including web server and web service for functional annotation and enrichment analyses of gene lists. Consists of comprehensive knowledgebase and set of functional analysis tools. Includes gene centered database integrating heterogeneous gene annotation resources to facilitate high throughput gene functional analysis.

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Addgene (tool)

RRID:SCR_002037

Non-profit plasmid repository dedicated to helping scientists around the world share high-quality plasmids. Facilitates archiving and distributing DNA-based research reagents and associated data to scientists worldwide. Repository contains over 65,000 plasmids, including special collections on CRISPR, fluorescent proteins, and ready-to-use viral preparations. There is no cost for scientists to deposit plasmids, which saves time and money associated with shipping plasmids themselves. All plasmids are fully sequenced for validation and sequencing data is openly available. We handle the appropriate Material Transfer Agreements (MTA) with institutions, facilitating open exchange and offering intellectual property and liability protection for depositing scientists. Furthermore, we curate free educational resources for the scientific community including a blog, eBooks, video protocols, and detailed molecular biology resources.

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FlowJo (tool)

RRID:SCR_008520

Software for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.

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Bethyl (tool)

RRID:SCR_013554

An Antibody supplier

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Agilent Technologies (tool)

RRID:SCR_013575

Company provides laboratories worldwide with analytical instruments and supplies, clinical and diagnostic testing services, consumables, applications and expertise in life sciences and applied chemical markets.

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A-549 (tool)

RRID:CVCL_0023

Cell line A-549 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HCT 116 (tool)

RRID:CVCL_0291

Cell line HCT 116 is a Cancer cell line with a species of origin Homo sapiens (Human)

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p53HCT116 (tool)

RRID:CVCL_S744

Cell line p53HCT116 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HEK293-FT (tool)

RRID:CVCL_6911

Cell line HEK293-FT is a Transformed cell line with a species of origin Homo sapiens (Human)

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Eg5 antibody (antibody)

RRID:AB_10640358

This polyclonal targets Eg5 antibody

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cdc2 Antibody (antibody)

RRID:AB_10693432

This unknown targets cdc2

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Rabbit IgG Monoclonal Antibody ; Isotype Control, Alexa Fluor?? 488 Conjugate Conjugated, Clone DA1E (antibody)

RRID:AB_10699151

This monoclonal targets Rabbit IgG ; Isotype Control Alexa Fluor?? 488 Conjugate Clone DA1E

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EZH2 (antibody)

RRID:AB_2102429

This monoclonal targets EZH2

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Monoclonal Anti-alpha-Tubulin antibody produced in mouse (antibody)

RRID:AB_477582

This monoclonal targets alpha-Tubulin antibody produced in mouse

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TP53-human (antibody)

RRID:AB_628082

This monoclonal targets TP53

View all literature mentions

ATR Antibody (antibody)

RRID:AB_2063318

This unknown targets ATR

View all literature mentions

Stathmin (antibody)

RRID:AB_991829

This monoclonal targets Stmn1

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ATM Phospho (pS1981) (antibody)

RRID:AB_991678

This monoclonal targets ATM Phospho (pS1981)

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ATM antibody [Y170] (antibody)

RRID:AB_725574

This monoclonal targets ATM antibody [Y170]

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Phospho-cdc2 (Tyr15) Antibody (antibody)

RRID:AB_331460

This unknown targets cdc2, phospho (Tyr15)

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Phospho-p53 (Ser15) Antibody (antibody)

RRID:AB_331464

This polyclonal targets Phospho-p53 (Ser15)

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PARP Antibody (antibody)

RRID:AB_2160739

This polyclonal targets PARP

View all literature mentions

Eg5 antibody (antibody)

RRID:AB_10640358

This polyclonal targets Eg5 antibody

View all literature mentions

cdc2 Antibody (antibody)

RRID:AB_10693432

This unknown targets cdc2

View all literature mentions

Rabbit IgG Monoclonal Antibody ; Isotype Control, Alexa Fluor?? 488 Conjugate Conjugated, Clone DA1E (antibody)

RRID:AB_10699151

This monoclonal targets Rabbit IgG ; Isotype Control Alexa Fluor?? 488 Conjugate Clone DA1E

View all literature mentions

EZH2 (antibody)

RRID:AB_2102429

This monoclonal targets EZH2

View all literature mentions

Monoclonal Anti-alpha-Tubulin antibody produced in mouse (antibody)

RRID:AB_477582

This monoclonal targets alpha-Tubulin antibody produced in mouse

View all literature mentions

TP53-human (antibody)

RRID:AB_628082

This monoclonal targets TP53

View all literature mentions

ATR Antibody (antibody)

RRID:AB_2063318

This unknown targets ATR

View all literature mentions

Stathmin (antibody)

RRID:AB_991829

This monoclonal targets Stmn1

View all literature mentions

ATM Phospho (pS1981) (antibody)

RRID:AB_991678

This monoclonal targets ATM Phospho (pS1981)

View all literature mentions

ATM antibody [Y170] (antibody)

RRID:AB_725574

This monoclonal targets ATM antibody [Y170]

View all literature mentions

Phospho-cdc2 (Tyr15) Antibody (antibody)

RRID:AB_331460

This unknown targets cdc2, phospho (Tyr15)

View all literature mentions

Phospho-p53 (Ser15) Antibody (antibody)

RRID:AB_331464

This polyclonal targets Phospho-p53 (Ser15)

View all literature mentions

PARP Antibody (antibody)

RRID:AB_2160739

This polyclonal targets PARP

View all literature mentions