We generated human induced pluripotent stem cells (hiPSCs) from dermal fibroblasts of a 51years old female patient homozygous for the mutation c.535 G>A p.G179S on the KCNQ1 gene, causing a severe form of autosomal recessive Long QT Syndrome type 1 (AR-LQT1), not associated with deafness. The hiPSCs, generated using four retroviruses each encoding for a reprogramming factor OCT4, SOX2, KLF4, cMYC, are pluripotent and can differentiate into spontaneously beating cardiomyocytes (hiPSC-CMs).
Pubmed ID: 29684900 RIS Download
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This unknown targets Mouse IgG (H+L)
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View all literature mentionsThis unknown targets Alpha-1-Fetoprotein (AFP, a-Fetoprotein) / Actin, Smooth muscle / Troponin I, Cardiac (cTnI) / Nestin
View all literature mentionsThis unknown targets Alpha-1-Fetoprotein (AFP, a-Fetoprotein) / Actin, Smooth muscle / Troponin I, Cardiac (cTnI) / Nestin
View all literature mentions