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ASPP2 Inhibits the Profibrotic Effects of Transforming Growth Factor-β1 in Hepatic Stellate Cells by Reducing Autophagy.

Digestive diseases and sciences | 2018

Apoptosis-stimulating protein of p53-2 (ASPP2) is a damage-inducible P53-binding protein that enhances damage-induced apoptosis. Fibrosis is a wound-healing response, and hepatic stellate cells (HSCs) are key players in liver fibrogenesis. However, little is known about the relationship between ASPP2 and hepatic fibrosis.

Pubmed ID: 29196956 RIS Download

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Associated grants

  • Agency: the National Natural and Science Foundation of China, International
    Id: 81672026
  • Agency: Basics-Clinical Research Cooperation Fund of Capital Medical University,China, International
    Id: 15JL-L05
  • Agency: Beijing Municipal Institute of Public Medical Research Development and Reform Pilot Project, International
    Id: (JING YI YAN 2016-2)

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PeproTech (tool)

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