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Publication

RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination.

BMC biology | 2017

TRIM25 is a novel RNA-binding protein and a member of the Tripartite Motif (TRIM) family of E3 ubiquitin ligases, which plays a pivotal role in the innate immune response. However, there is scarce knowledge about its RNA-related roles in cell biology. Furthermore, its RNA-binding domain has not been characterized.

Pubmed ID: 29117863 RIS Download

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Associated grants

Agency: Medical Research Council, United Kingdom
Id: MR/K001744/1
Agency: Medical Research Council, United Kingdom
Id: MR/L019434/1
Agency: Biotechnology and Biological Sciences Research Council, United Kingdom
Id: BB/J004243/1
Agency: Wellcome Trust, United Kingdom
Id: 084229
Agency: Wellcome Trust, United Kingdom
Id: 103139/Z/13/Z
Agency: Wellcome Trust, United Kingdom
Id: 091549
Agency: Wellcome Trust, United Kingdom
Id: 105246
Agency: Wellcome Trust, United Kingdom
Id: 077707
Agency: Wellcome Trust, United Kingdom
Agency: Medical Research Council, United Kingdom
Id: MC_UU_12014/10
Agency: Wellcome Trust, United Kingdom
Id: 096996
Agency: Wellcome Trust, United Kingdom
Id: 091020
Agency: Medical Research Council, United Kingdom
Id: G1000564
Agency: Wellcome Trust, United Kingdom
Id: 092076

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RRID:SCR_010236

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