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The relationship between specific genome alterations and hepatocellular carcinoma (HCC) cancer stem cells (CSCs) remains unclear. In this study, we evaluated the relationship between somatic mutations and epithelial cell adhesion molecule positive (EpCAM+) CSCs.
Pubmed ID: 29075151 RIS Download
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A tool to design target-specific primers for polymerase chain reaction (PCR). It uses Primer3 to design PCR primers and then uses BLAST and global alignment algorithm to screen primers against user-selected database in order to avoid primer pairs (all combinations including forward-reverse primer pair, forward-forward as well as reverse-reverse pairs) that can cause non-specific amplifications.
View all literature mentionsSoftware tool which predicts possible impact of amino acid substitution on structure and function of human protein using straightforward physical and comparative considerations. PolyPhen-2 is new development of PolyPhen tool for annotating coding nonsynonymous SNPs.
View all literature mentionsCommercial organism provider selling mice, rats and other model animals. American corporation specializing in a variety of pre-clinical and clinical laboratory services for the pharmaceutical, medical device and biotechnology industries. It also supplies assorted biomedical products and research and development outsourcing services for use in the pharmaceutical industry. (Wikipedia)
View all literature mentionsData analysis service to predict whether an amino acid substitution affects protein function based on sequence homology and the physical properties of amino acids. SIFT can be applied to naturally occurring nonsynonymous polymorphisms and laboratory-induced missense mutations. (entry from Genetic Analysis Software) Web service is also available.
View all literature mentionsCell line Huh-7 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HLF is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HLE is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line Hep 3B2.1-7 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line SK-HEP-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line PLC/PRF/5 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HuH-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line PLC/PRF/5 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line SK-HEP-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line Hep 3B2.1-7 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HLF is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HLE is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line Huh-7 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HuH-1 is a Cancer cell line with a species of origin Homo sapiens (Human)
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