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Intravascular leukocyte recruitment in most vertebrate tissues is restricted to postcapillary and collecting venules, whereas capillaries and arterioles usually support little or no leukocyte adhesion. This segmental restriction is thought to be mediated by endothelial, rather than hemodynamic, differences. The underlying mechanisms are largely unknown, in part because effective tools to distinguish, isolate, and analyze venular endothelial cells (V-ECs) and non-venular endothelial cells (NV-ECs) have been unavailable. We hypothesized that the atypical chemokine receptor DARC (Duffy Antigen Receptor for Chemokines, a.k.a. ACKR1 or CD234) may distinguish V-ECs versus NV-ECs in mice.
Pubmed ID: 28526034 RIS Download
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Cell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
View all literature mentionsCell line PC12 is a Cancer cell line with a species of origin Rattus norvegicus
View all literature mentionslaboratory mouse with name BALB/cAnNCrl from MGI.
View all literature mentionsThis monoclonal targets Armenian Hamster IgG Isotype Control PE Clone HTK888
View all literature mentionsThis monoclonal targets Trinitrophenol + KLH
View all literature mentionsThis monoclonal targets CD31
View all literature mentionsThis monoclonal targets CD45
View all literature mentionsThis monoclonal targets CD31
View all literature mentionsThis monoclonal targets CD45
View all literature mentionsThis monoclonal targets CD45.2
View all literature mentionsThis monoclonal targets CD45.2
View all literature mentionsThis monoclonal targets TER-119
View all literature mentionsThis monoclonal targets TER-119
View all literature mentionsThis monoclonal targets Podoplanin
View all literature mentionsThis monoclonal targets CD54
View all literature mentionsThis monoclonal targets CD31
View all literature mentionsThis unknown targets Rat
View all literature mentionsThis monoclonal targets MAdCAM-1
View all literature mentionsThis monoclonal targets High Endothelial Venule Marker
View all literature mentionsThis monoclonal targets CD31
View all literature mentionsThis monoclonal targets beta-Actin
View all literature mentionsThis polyclonal targets rat IgG HRP-linked
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsSoftware for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.
View all literature mentionsImaris provides range of capabilities for working with three dimensional images. Uses flexible editing and processing functions, such as interactive surface rendering and object slicing capabilities. And output to standard TIFF, Quicktime and AVI formats. Imaris accepts virtually all image formats that are used in confocal microscopy and many of those used in wide-field image acquisition.
View all literature mentionsMus musculus with name B6.129P2-Apoetm1Unc/J from IMSR.
View all literature mentionsMus musculus with name BALB/cJ from IMSR.
View all literature mentionsThis monoclonal targets beta-Actin
View all literature mentionsThis polyclonal targets rat IgG HRP-linked
View all literature mentionsMus musculus with name B6.129P2-Apoetm1Unc/J from IMSR.
View all literature mentionsMus musculus with name BALB/cJ from IMSR.
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
View all literature mentionsThis monoclonal targets Armenian Hamster IgG Isotype Control PE Clone HTK888
View all literature mentionsThis monoclonal targets Trinitrophenol + KLH
View all literature mentionsStatistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.
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