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Growth/differentiation factor 8 (GDF8) and GDF11 are two highly similar members of the transforming growth factor β (TGFβ) family. While GDF8 has been recognized as a negative regulator of muscle growth and differentiation, there are conflicting studies on the function of GDF11 and whether GDF11 has beneficial effects on age-related dysfunction. To address whether GDF8 and GDF11 are functionally identical, we compared their signaling and structural properties.
Pubmed ID: 28257634 RIS Download
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A commercial antibody supplier and provider of various services.
View all literature mentionsA Python-based software suite for the automated determination of molecular structures using X-ray crystallography and other methods. Phenix includes programs for assessing data quality, experimental phasing, molecular replacement, model building, structure refinement, and validation. It also includes tools for reflection data and creating maps and models. Phenix can also be used for neutron crystallography. Tutorials and examples are available in the documentation tab.
View all literature mentionsAnalysis software for life science data. This software package is for presentation and evaluation of sensorgram data from real-time BIA analyses.
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
View all literature mentionsCell line R1B-L17 is a Spontaneously immortalized cell line with a species of origin Neovison vison (American mink)
View all literature mentionsCell line LbetaT2 is a Transformed cell line with a species of origin Mus musculus
View all literature mentionsCell line Hep-G2 is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line R1B-L17 is a Spontaneously immortalized cell line with a species of origin Neovison vison (American mink)
View all literature mentionsThe SciCrunch Infrastructure was developed as a cooperative data platform to be used by diverse communities in making data more FAIR.
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