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Vaginal estrogen: a dual-edged sword in postoperative healing of the vaginal wall.

Menopause (New York, N.Y.) | 2017

Reconstructive surgery for pelvic organ prolapse is plagued with high failure rates possibly due to impaired healing or regeneration of the vaginal wall. Here, we tested the hypothesis that postoperative administration of local estrogen, direct injection of mesenchymal stem cells (MSCs), or both lead to improved wound healing of the injured vagina in a menopausal rat model.

Pubmed ID: 28169915 RIS Download

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Associated grants

  • Agency: NIA NIH HHS, United States
    Id: R01 AG028048
  • Agency: NIA NIH HHS, United States
    Id: R01 AG047290
  • Agency: NICHD NIH HHS, United States
    Id: R01 HD064824

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