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Increased amygdala reactivity following early life stress: a potential resilience enhancer role.

BMC psychiatry | 2017

Amygdala hyper-reactivity is sometimes assumed to be a vulnerability factor that predates depression; however, in healthy people, who experience early life stress but do not become depressed, it may represent a resilience mechanism. We aimed to test these hypothesis examining whether increased amygdala activity in association with a history of early life stress (ELS) was negatively or positively associated with depressive symptoms and impact of negative life event stress in never-depressed adults.

Pubmed ID: 28100219 RIS Download

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Associated grants

  • Agency: NIMH NIH HHS, United States
    Id: R01 MH096334

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WFU PickAtlas (tool)

RRID:SCR_007378

A software toolbox that provides a method for generating Region of Interest (ROI) masks based on the Talairach Daemon database. The atlases include Brodmann area, Lobar, Hemisphere, Anatomic Label (gyral anatomy), and Tissue type. The atlases have been extended to the vertex in MNI space, and corrected for the precentral gyrus anomaly. Additional atlases (including non-human atlases) can be added without difficulty.

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