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Hippocampal volume predicts antidepressant efficacy in depressed patients without incomplete hippocampal inversion.

NeuroImage. Clinical | 2016

Incomplete hippocampal inversion (IHI), also called malrotation, is a frequent atypical anatomical pattern of the hippocampus. Because of the crucial implication of the hippocampus in Major Depressive Disorder (MDD) and the neurodevelopmental hypothesis of MDD, we aimed to assess the prevalence of IHI in patients with MDD, the link of IHI with hippocampal volume (HV) and the impact of IHI on the predictive value of HV for response and remission after antidepressant treatment.

Pubmed ID: 27995060 RIS Download

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