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In vivo inhibition of miR-155 significantly alters post-stroke inflammatory response.

Journal of neuroinflammation | 2016

MicroRNA miR-155 is implicated in modulation of the inflammatory processes in various pathological conditions. In our previous studies, we demonstrated that in vivo inhibition of miR-155 promotes functional recovery after mouse experimental stroke. In the present study, we explored if this beneficial effect is associated with miR-155 inhibition-induced alterations in post-stroke inflammatory response.

Pubmed ID: 27829437 RIS Download

Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: R01 NS082225

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This is a list of tools and resources that we have found mentioned in this publication.


Ambion Inc. (tool)

RRID:SCR_008406

A division of Applied Biosystems selling products for the isolation, detection, quantification, amplification, and characterization of RNA.

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Bio-Rad Laboratories (tool)

RRID:SCR_008426

Commercial instrument and chemical vendor. Developer and manufacturer of specialized technological products for life science research and clinical diagnostics markets.

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BioRad Helios Gene Delivery System (tool)

RRID:SCR_019723

Handheld gene delivery system that provides direct transfection into a range of targets in vivo. It uses adjustable low pressure helium pulse to sweep DNA, RNA, or biomaterial coated gold microcarriers from a plastic cartridge directly into target cells.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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Anti Iba1, Rabbit antibody (antibody)

RRID:AB_839504

This polyclonal targets Iba1

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Anti-NeuN (rabbit polyclonal), Cy3 Conjugate (antibody)

RRID:AB_11204707

This polyclonal targets NeuN (rabbit polyclonal) Cy3 Conjugate

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CD68 antibody | FA-11 (antibody)

RRID:AB_322219

This monoclonal targets CD68

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SOCS-6 (H-251) (antibody)

RRID:AB_661195

This polyclonal targets SOCS6

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C/EBP-beta (LAP) Antibody (antibody)

RRID:AB_2078052

This polyclonal targets Cebpb

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SHIP1 (D1163) Antibody (antibody)

RRID:AB_2126244

This polyclonal targets Inpp5d

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SOCS1 (A156) Antibody (antibody)

RRID:AB_2192983

This polyclonal targets SOCS1 (A156)

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Stat3 (124H6) Mouse mAb (antibody)

RRID:AB_331757

This monoclonal targets Stat3

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NIH Image (software resource)

RRID:SCR_003073

Public image processing and analysis program for Macintosh.

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PRISM (data analysis service)

RRID:SCR_005375

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 5,2022.Tool that predicts interactions between transcription factors and their regulated genes from binding motifs. Understanding vertebrate development requires unraveling the cis-regulatory architecture of gene regulation. PRISM provides accurate genome-wide computational predictions of transcription factor binding sites for the human and mouse genomes, and integrates the predictions with GREAT to provide functional biological context. Together, accurate computational binding site prediction and GREAT produce for each transcription factor: 1. putative binding sites, 2. putative target genes, 3. putative biological roles of the transcription factor, and 4. putative cis-regulatory elements through which the factor regulates each target in each functional role.

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GraphPad Prism (software resource)

RRID:SCR_002798

Statistical analysis software that combines scientific graphing, comprehensive curve fitting (nonlinear regression), understandable statistics, and data organization. Designed for biological research applications in pharmacology, physiology, and other biological fields for data analysis, hypothesis testing, and modeling.

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Anti Iba1, Rabbit antibody (antibody)

RRID:AB_839504

This polyclonal targets Iba1

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NIH Image (software resource)

RRID:SCR_003073

Public image processing and analysis program for Macintosh.

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NIH Image (software resource)

RRID:SCR_003073

Public image processing and analysis program for Macintosh.

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Anti Iba1, Rabbit antibody (antibody)

RRID:AB_839504

This polyclonal targets Iba1

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Anti Iba1, Rabbit antibody (antibody)

RRID:AB_839504

This polyclonal targets Iba1

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NIH Image (software resource)

RRID:SCR_003073

Public image processing and analysis program for Macintosh.

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