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Muscle wasting and adipose tissue browning in infantile nephropathic cystinosis.

Journal of cachexia, sarcopenia and muscle | 2016

Muscle wasting is a common complication in patients with infantile nephropathic cystinosis, but its mechanism and association with energy metabolism is not known. We define the metabolic phenotype in Ctns(-/-) mice, an established murine model of infantile nephropathic cystinosis, with focus on muscle wasting and energy homeostasis.

Pubmed ID: 27493869 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK090058
  • Agency: NIDDK NIH HHS, United States
    Id: R01 DK099338

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PrimerBank (tool)

RRID:SCR_006898

Database of human and mouse primer pairs for gene expression analysis by polymerase chain reaction (PCR) and quantitative PCR (qPCR). A total of 306,800 primers covering most known human and mouse genes can be accessed from the PrimerBank database, together with information on these primers such as T(m), location on the transcript and amplicon size. For each gene, at least one primer pair has been designed and in many cases alternative primer pairs exist. Primers have been designed to work under the same PCR conditions, thus facilitating high-throughput QPCR. All primers in PrimerBank were carefully designed to ensure gene specificity. All experimental validation data for mouse primers are available from PrimerBank. You can submit your primers. They will be added to the database once they are properly QCd.

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RayBiotech (tool)

RRID:SCR_005517

An Antibody supplier

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Ctnstm1Antc/Ctnstm1Antc (tool)

RRID:MGI:2672886

Allele Detail: Targeted This is a legacy resource.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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