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Apolipoprotein E (ApoE) is a major lipid carrier that supports lipid transport and injury repair in the brain. The APOE ε4 allele is associated with depression, mild cognitive impairment (MCI) and dementia; however, the precise molecular mechanism through which ApoE4 influences the risk of disease development remains unknown. To address this gap in knowledge, we investigated the potential effects of chronic unpredictable mild stress (CUMS) on ApoE3 and ApoE4 target replacement (ApoE3-TR and ApoE4-TR) mice.
Pubmed ID: 27406263 RIS Download
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THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18,2023. Platform that delivers software tools to capture, process, measure, analyze and share images and data for scientific and industrial imaging community. Used for image-based data collection and analysis to increase accuracy and automate research, development, and quality processes.
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View all literature mentionsTHIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18,2023. Platform that delivers software tools to capture, process, measure, analyze and share images and data for scientific and industrial imaging community. Used for image-based data collection and analysis to increase accuracy and automate research, development, and quality processes.
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
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