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Histone deacetylase inhibitor-induced cancer stem cells exhibit high pentose phosphate pathway metabolism.

Oncotarget | 2016

We recently demonstrated that histone deacetylase (HDAC) inhibitors can "reprogram" differentiated triple-negative breast cancer cells to become quiescent stem-like cancer cells. We hypothesized that the metabolic state of such cells differs from that of their differentiated progeny.

Pubmed ID: 27078845 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: P30 CA016672
  • Agency: NCI NIH HHS, United States
    Id: R01 CA138239
  • Agency: NCI NIH HHS, United States
    Id: R01 CA180061

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