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Muscular dystrophy in the mdx mouse is a severe myopathy compounded by hypotrophy, hypertrophy and hyperplasia.

Skeletal muscle | 2015

Preclinical testing of potential therapies for Duchenne muscular dystrophy (DMD) is conducted predominantly of the mdx mouse. But lack of a detailed quantitative description of the pathology of this animal limits our ability to evaluate the effectiveness of putative therapies or their relevance to DMD.

Pubmed ID: 25987977 RIS Download

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Associated grants

  • Agency: NIH HHS, United States
    Id: K26 OD011171
  • Agency: NINDS NIH HHS, United States
    Id: R01 NS029525
  • Agency: NICHD NIH HHS, United States
    Id: U54 HD053177
  • Agency: NICHD NIH HHS, United States
    Id: R24 HD050846
  • Agency: NIAMS NIH HHS, United States
    Id: P50 AR060836

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AxioVision Imaging System (tool)

RRID:SCR_002677

Digital image processing system where microscope settings and processing steps may be adjusted in single user interface. Can acquire images from variety of cameras. Includes software package for capturing, archiving and preparing images for publication. Allows users to visualize and present images in several dimensions. Functionality of imaging toolbox expands constantly with wide range of different modules that are tailored to specific applications or microscope accessories. This resource is duplicated by SCR_018376

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