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High fat diet modulates Trypanosoma cruzi infection associated myocarditis.

PLoS neglected tropical diseases | 2014

Trypanosoma cruzi, the causative agent of Chagas disease, has high affinity for lipoproteins and adipose tissue. Infection results in myocarditis, fat loss and alterations in lipid homeostasis. This study was aimed at analyzing the effect of high fat diet (HFD) on regulating acute T. cruzi infection-induced myocarditis and to evaluate the effect of HFD on lipid metabolism in adipose tissue and heart during acute T. cruzi infection.

Pubmed ID: 25275627 RIS Download

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Associated grants

  • Agency: NHLBI NIH HHS, United States
    Id: R21 HL112099
  • Agency: NCRR NIH HHS, United States
    Id: S10 RR029545

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C3H/HeJ (tool)

RRID:IMSR_JAX:000659

Mus musculus with name C3H/HeJ from IMSR.

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Crl:CD1(ICR) (tool)

RRID:IMSR_CRL:022

Mus musculus with name Crl:CD1(ICR) from IMSR.

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