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HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.

Retrovirology | 2014

We have shown that HIV-1 Tat interaction with MAP2K3, MAP2K6, and IRF7 promoters is key to IFN-stimulated genes (ISG) activation in immature dendritic cells and macrophages.

Pubmed ID: 24742347 RIS Download

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Associated grants

  • Agency: NIMH NIH HHS, United States
    Id: R01 MH095671

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