Cardiac function depends on the highly regulated and co-ordinate activity of a large ensemble of potassium channels that control myocyte repolarization. While voltage-gated K(+) channels have been well characterized in the heart, much less is known about regulation and/or targeting of two-pore K(+) channel (K(2P)) family members, despite their potential importance in modulation of heart function.
Pubmed ID: 24445605 RIS Download
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This monoclonal targets Kvbeta1.2 potassium channel
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View all literature mentionsThis monoclonal targets Kv2.1 K+ channel
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