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Exome sequencing is increasingly used to search for phenotypically-relevant sequence variants in the mouse genome. All of the current hybridization-based mouse exome capture systems are designed based on the genome reference sequences of the C57BL/6 J strain. Given that the substantial sequence divergence exists between C57BL/6 J and other distantly-related strains, the impact of sequence divergence on the efficiency of such capture systems needs to be systematically evaluated before they can be widely applied to the study of those strains.
Pubmed ID: 23870319 RIS Download
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Java toolset for working with next generation sequencing data in the BAM format.
View all literature mentionsFTP site to access Schizosaccharomyces pombe protein data.
View all literature mentionsMus musculus with name C57BL/6J from IMSR.
View all literature mentionsMus musculus with name SPRET/EiJ from IMSR.
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