Ciliated cells play a central role in cleansing the airways of inhaled contaminants. They are derived from basal cells that include the airway stem/progenitor cells. In animal models, the transcription factor FOXJ1 has been shown to induce differentiation to the ciliated cell lineage, and the RFX transcription factor-family has been shown to be necessary for, but not sufficient to induce, correct cilia development.
Pubmed ID: 23822649 RIS Download
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Cell line HEK293-A is a Transformed cell line with a species of origin Homo sapiens (Human)
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