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The Caenorhabditis elegans voltage-gated calcium channel subunits UNC-2 and UNC-36 and the calcium-dependent kinase UNC-43/CaMKII regulate neuromuscular junction morphology.

Neural development | 2013

The conserved Caenorhabditis elegans proteins NID-1/nidogen and PTP-3A/LAR-RPTP function to efficiently localize the presynaptic scaffold protein SYD-2/α-liprin at active zones. Loss of function in these molecules results in defects in the size, morphology and spacing of neuromuscular junctions.

Pubmed ID: 23663262 RIS Download

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Associated grants

  • Agency: NCRR NIH HHS, United States
    Id: P20 RR016475
  • Agency: Howard Hughes Medical Institute, United States
  • Agency: NINDS NIH HHS, United States
    Id: NS035546
  • Agency: NIGMS NIH HHS, United States
    Id: P20 GM103638
  • Agency: NIGMS NIH HHS, United States
    Id: RC1 GM091086

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Olympus Fluoview FV10-ASW (tool)

RRID:SCR_014215

Image processing software used to modify and clarify sample images for FluoView FV1000 range of confocal laser scanning microscopes and Fluoview FV1000MPE multiphoton excitation systems. The software incorporates high-dynamic-range imaging, minimized signal-to-noise ratios, partial stitching with multiarea time-lapse imaging, and channel unmixing. The software also allows users to select specific areas of the whole sample, which can stitched together.

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VC550 (tool)

RRID:WB-STRAIN:WBStrain00035865

Caenorhabditis elegans with name tag-180(ok779) II. from WB.

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