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The interaction of Kinesin-1 with its adaptor protein JIP1 can be regulated via proteins binding to the JIP1-PTB domain.

BMC cell biology | 2013

The regulatory mechanisms of motor protein-dependent intracellular transport are still not fully understood. The kinesin-1-binding protein, JIP1, can function as an adaptor protein that links kinesin-1 and other JIP1-binding "cargo" proteins. However, it is unknown whether these "cargo" proteins influence the JIP1-kinesin-1 binding.

Pubmed ID: 23496950 RIS Download

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Neuro-2a (tool)

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HEK293T (tool)

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Cell line HEK293T is a Transformed cell line with a species of origin Homo sapiens (Human)

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