Glial cell line-derived neurotrophic factor (GDNF) family ligands are secreted growth factors distantly related to the TGF-β superfamily. In mammals, they bind to the GDNF family receptor α (Gfrα) and signal through the Ret receptor tyrosine kinase. In order to gain insight into the evolution of the Ret-Gfr-Gdnf signaling system, we have cloned and characterized the first invertebrate Gfr-like cDNA (DmGfrl) from Drosophila melanogaster and generated a DmGfrl mutant allele.
Pubmed ID: 23284846 RIS Download
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This polyclonal targets Gfrl
View all literature mentionsThis monoclonal targets Mouse Drosophila fasciclin II
View all literature mentionsThis monoclonal targets Repo; Reversed polarity protein
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