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The study of muscle remodeling in Drosophila metamorphosis using in vivo microscopy and bioimage informatics.

BMC bioinformatics | 2012

Metamorphosis in insects transforms the larval into an adult body plan and comprises the destruction and remodeling of larval and the generation of adult tissues. The remodeling of larval into adult muscles promises to be a genetic model for human atrophy since it is associated with dramatic alteration in cell size. Furthermore, muscle development is amenable to 3D in vivo microscopy at high cellular resolution. However, multi-dimensional image acquisition leads to sizeable amounts of data that demand novel approaches in image processing and analysis.

Pubmed ID: 23282138 RIS Download

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OpenCV (tool)

RRID:SCR_015526

Computer vision and machine learning software library which provides a common infrastructure for computer vision applications. The algorithms within the library can be used to detect and recognize faces, identify objects, classify human actions in videos, track camera movements and moving objects, extract 3D models of objects, produce 3D point clouds from stereo cameras, stitch images together to produce a high resolution image of an entire scene, find similar images from an image database, and follow eye movements, recognize scenery and establish markers to overlay it with augmented reality. It has C++, C, Python, Java and MATLAB interfaces.

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w[*]; P{w[+m*]=Mef2-GAL4.247}3 (tool)

RRID:BDSC_50742

Drosophila melanogaster with name w[*]; P{w[+m*]=Mef2-GAL4.247}3 from BDSC.

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