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Accessing data from the International Mouse Phenotyping Consortium: state of the art and future plans.

The International Mouse Phenotyping Consortium (IMPC) (http://www.mousephenotype.org) will reveal the pleiotropic functions of every gene in the mouse genome and uncover the wider role of genetic loci within diverse biological systems. Comprehensive informatics solutions are vital to ensuring that this vast array of data is captured in a standardised manner and made accessible to the scientific community for interrogation and analysis. Here we review the existing EuroPhenome and WTSI phenotype informatics systems and the IKMC portal, and present plans for extending these systems and lessons learned to the development of a robust IMPC informatics infrastructure.

Pubmed ID: 22991088

Authors

  • Mallon AM
  • Iyer V
  • Melvin D
  • Morgan H
  • Parkinson H
  • Brown SD
  • Flicek P
  • Skarnes WC

Journal

Mammalian genome : official journal of the International Mammalian Genome Society

Publication Data

October 11, 2012

Associated Grants

  • Agency: Medical Research Council, Id: MC_U142684171
  • Agency: Medical Research Council, Id: MC_U142684172
  • Agency: Medical Research Council, Id: MC_U142684175
  • Agency: NHGRI NIH HHS, Id: U54 HG006370

Mesh Terms

  • Animals
  • Internationality
  • Mice
  • Phenotype