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The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.

Determining the function of all mammalian genes remains a major challenge for the biomedical science community in the 21st century. The goal of the International Mouse Phenotyping Consortium (IMPC) over the next 10 years is to undertake broad-based phenotyping of 20,000 mouse genes, providing an unprecedented insight into mammalian gene function. This short article explores the drivers for large-scale mouse phenotyping and provides an overview of the aims and processes involved in IMPC mouse production and phenotyping.

Pubmed ID: 22940749

Authors

  • Brown SD
  • Moore MW

Journal

Mammalian genome : official journal of the International Mammalian Genome Society

Publication Data

October 11, 2012

Associated Grants

  • Agency: Medical Research Council, Id: MC_U142684172
  • Agency: Medical Research Council, Id: MC_U142684175
  • Agency: NIH HHS, Id: U42 OD011174
  • Agency: NHGRI NIH HHS, Id: U54 HG006348

Mesh Terms

  • Animals
  • Internationality
  • Mice
  • Mice, Mutant Strains
  • Phenotype