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Genetic modification is a prerequisite to realizing the full potential of human embryonic stem cells (hESCs) in human genetic research and regenerative medicine. Unfortunately, the random integration methods that have been the primary techniques used keep creating problems, and the primary alternative method, gene targeting, has been effective in manipulating mouse embryonic stem cells (mESCs) but poorly in hESCs.
Pubmed ID: 22615895 RIS Download
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Cell line HT-1080 is a Cancer cell line with a species of origin Homo sapiens (Human)
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