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An MRI study of amygdala in schizophrenia and psychotic bipolar disorder.

Schizophrenia research | Jul 11, 2012

http://www.ncbi.nlm.nih.gov/pubmed/22559949

Meta-analyses report larger amygdala in subjects with bipolar disorder compared to schizophrenia. However, few studies have compared the size of amygdala in psychotic bipolar disorder with schizophrenia. Here we examine size of amygdala in a sample of 36 patients with psychotic bipolar disorder, 31 patients with schizophrenia and 27 healthy comparison subjects. Patients with schizophrenia had smaller amygdala compared with patients with psychotic bipolar disorder (p=0.014). These results suggest that change in volume of amygdala may represent a morphologic feature distinguishing psychotic bipolar disorder from schizophrenia.

Pubmed ID: 22559949 RIS Download

Mesh terms: Adult | Amygdala | Bipolar Disorder | Case-Control Studies | Female | Humans | Magnetic Resonance Imaging | Male | Middle Aged | Organ Size | Schizophrenia

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