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The origin of malarial parasites in orangutans.

PloS one | 2012

Recent findings of Plasmodium in African apes have changed our perspectives on the evolution of malarial parasites in hominids. However, phylogenetic analyses of primate malarias are still missing information from Southeast Asian apes. In this study, we report molecular data for a malaria parasite lineage found in orangutans.

Pubmed ID: 22536346 RIS Download

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Associated grants

  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM080586
  • Agency: NIGMS NIH HHS, United States
    Id: R01 GM084320
  • Agency: NIGMS NIH HHS, United States
    Id: GM084320

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BEAST (tool)

RRID:SCR_010228

A cross-platform software program for Bayesian MCMC analysis of molecular sequences. It is entirely orientated towards rooted, time-measured phylogenies inferred using strict or relaxed molecular clock models. It can be used as a method of reconstructing phylogenies but is also a framework for testing evolutionary hypotheses without conditioning on a single tree topology. BEAST uses MCMC to average over tree space, so that each tree is weighted proportional to its posterior probability. We include a simple to use user-interface program for setting up standard analyses and a suit of programs for analysing the results.

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