Neocortical circuits are established through the formation of synapses between cortical neurons, but the molecular mechanisms of synapse formation are only beginning to be understood. The mechanisms that control synaptic vesicle (SV) and active zone (AZ) protein assembly at developing presynaptic terminals have not yet been defined. Similarly, the role of glutamate receptor activation in control of presynaptic development remains unclear.
Pubmed ID: 22340949 RIS Download
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Cell line HEK293 is a Transformed cell line with a species of origin Homo sapiens (Human)
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