• Register
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.


Leaving Community

Are you sure you want to leave this community? Leaving the community will revoke any permissions you have been granted in this community.


SynaptomeDB: an ontology-based knowledgebase for synaptic genes.

MOTIVATION: The synapse is integral to the function of the brain and may be an important source of dysfunction underlying many neuropsychiatric disorders. Consequently, it is an excellent candidate for large-scale genomic and proteomic study. However, while the tools and databases available for the annotation of high-throughput DNA and protein are generally robust, a comprehensive resource dedicated to the integration of information about the synapse is lacking. RESULTS: We present an integrated database, called SynaptomeDB, to retrieve and annotate genes comprising the synaptome. These genes encode components of the synapse including neurotransmitters and their receptors, adhesion/cytoskeletal proteins, scaffold proteins, membrane transporters. SynaptomeDB integrates various and complex data sources for synaptic genes and proteins.

Pubmed ID: 22285564


  • Pirooznia M
  • Wang T
  • Avramopoulos D
  • Valle D
  • Thomas G
  • Huganir RL
  • Goes FS
  • Potash JB
  • Zandi PP


Bioinformatics (Oxford, England)

Publication Data

March 15, 2012

Associated Grants

  • Agency: NIMH NIH HHS, Id: K01 MH093809
  • Agency: NIMH NIH HHS, Id: K01 MH093809-01
  • Agency: NIMH NIH HHS, Id: K01 MH093809-02
  • Agency: NIMH NIH HHS, Id: K01-MH093809
  • Agency: NIMH NIH HHS, Id: R01 MH087979
  • Agency: NIMH NIH HHS, Id: R01-MH083738
  • Agency: NIMH NIH HHS, Id: R01-MH087979

Mesh Terms

  • Databases, Genetic
  • Genomics
  • Humans
  • Internet
  • Knowledge Bases
  • Proteins
  • Synapses