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Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.

PloS one | 2012

Glucose increases the expression of glycolytic enzymes and other hypoxia-response genes in pancreatic beta-cells. Here, we tested whether this effect results from the activation of Hypoxia-Inducible-factors (HIF) 1 and 2 in a hypoxia-dependent manner.

Pubmed ID: 22235342 RIS Download

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INS-1E (tool)

RRID:CVCL_0351

Cell line INS-1E is a Cancer cell line with a species of origin Rattus norvegicus (Rat)

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WI (tool)

RRID:RGD_13508588

Rattus norvegicus with name WI from RGD.

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C57BLKS/J (tool)

RRID:IMSR_JAX:000662

Mus musculus with name C57BLKS/J from IMSR.

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