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The Gene Ontology: enhancements for 2011.

Nucleic acids research | 2012

The Gene Ontology (GO) (http://www.geneontology.org) is a community bioinformatics resource that represents gene product function through the use of structured, controlled vocabularies. The number of GO annotations of gene products has increased due to curation efforts among GO Consortium (GOC) groups, including focused literature-based annotation and ortholog-based functional inference. The GO ontologies continue to expand and improve as a result of targeted ontology development, including the introduction of computable logical definitions and development of new tools for the streamlined addition of terms to the ontology. The GOC continues to support its user community through the use of e-mail lists, social media and web-based resources.

Pubmed ID: 22102568 RIS Download

Research resources used in this publication

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Antibodies used in this publication

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Associated grants

  • Agency: NHGRI NIH HHS, United States
    Id: 5P41HG002273-09
  • Agency: NHGRI NIH HHS, United States
    Id: U41 HG002273
  • Agency: NCRR NIH HHS, United States
    Id: UL1 RR025741
  • Agency: NHGRI NIH HHS, United States
    Id: P41 HG001315
  • Agency: Wellcome Trust, United Kingdom
    Id: 090548
  • Agency: Medical Research Council, United Kingdom
    Id: G1000968
  • Agency: British Heart Foundation, United Kingdom
    Id: SP/07/007/23671

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This is a list of tools and resources that we have found mentioned in this publication.


AmiGO (tool)

RRID:SCR_002143

Web tool to search, sort, analyze, visualize and download data of interest. Along with providing details of the ontologies, gene products and annotations, features a BLAST search, Term Enrichment and GO Slimmer tools, the GO Online SQL Environment and a user help guide.Used at the Gene Ontology (GO) website to access the data provided by the GO Consortium. Developed and maintained by the GO Consortium.

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Gene Ontology (tool)

RRID:SCR_002811

Computable knowledge regarding functions of genes and gene products. GO resources include biomedical ontologies that cover molecular domains of all life forms as well as extensive compilations of gene product annotations to these ontologies that provide largely species-neutral, comprehensive statements about what gene products do. Used to standardize representation of gene and gene product attributes across species and databases.

View all literature mentions

GO Online SQL Environment (GOOSE) (tool)

RRID:SCR_006174

A web utility providing a direct interface to perform SQL queries directly on the GO database, allowing users to run custom queries without having to install a copy of the GO database locally. GOOSE includes many sample queries to aid novice users and allows results to be retrieved as a web page or as tab-delimited text. Platform: Online tool, Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible

View all literature mentions