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IL-21 is an antitolerogenic cytokine of the late-phase alloimmune response.

Diabetes | 2011

Interleukin-21 (IL-21) is a proinflammatory cytokine that has been shown to affect Treg/Teff balance. However, the mechanism by which IL-21 orchestrates alloimmune response and interplays with Tregs is still unclear.

Pubmed ID: 22013017 RIS Download

Research resources used in this publication

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: U01 AI082966
  • Agency: Intramural NIH HHS, United States
  • Agency: NIAID NIH HHS, United States
    Id: U01-AI-082966

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C57BL/6J (tool)

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