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Neuron-restrictive silencer factor-mediated hyperpolarization-activated cyclic nucleotide gated channelopathy in experimental temporal lobe epilepsy.

Annals of neurology | 2011

Enduring, abnormal expression and function of the ion channel hyperpolarization-activated cyclic adenosine monophosphate gated channel type 1 (HCN1) occurs in temporal lobe epilepsy (TLE). We examined the underlying mechanisms, and investigated whether interfering with these mechanisms could modify disease course.

Pubmed ID: 21905079 RIS Download

Research resources used in this publication

None found

Additional research tools detected in this publication

None found

Antibodies used in this publication

Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: T32 NS045540-06A1
  • Agency: NINDS NIH HHS, United States
    Id: T32 NS045540
  • Agency: NINDS NIH HHS, United States
    Id: T32 NS45540
  • Agency: NINDS NIH HHS, United States
    Id: R37 NS35439
  • Agency: NINDS NIH HHS, United States
    Id: R37 NS035439-10
  • Agency: NINDS NIH HHS, United States
    Id: R37 NS035439-11
  • Agency: NINDS NIH HHS, United States
    Id: R37 NS035439

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Anti-HCN2 Antibody (antibody)

RRID:AB_2279449

This monoclonal targets HCN2

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