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Polycomb group (PcG) genes code for chromatin multiprotein complexes that are responsible for maintaining gene silencing of transcriptional programs during differentiation and in adult tissues. Despite the large amount of information on PcG function during development and cell identity homeostasis, little is known regarding the dynamics of PcG complexes and their role during terminal differentiation.
Pubmed ID: 21892963 RIS Download
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Cell line C2C12 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)
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