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The CDC20 and Cdh1/CCS52 proteins are substrate determinants and activators of the Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligase and as such they control the mitotic cell cycle by targeting the degradation of various cell cycle regulators. In yeasts and animals the main CDC20 function is the destruction of securin and mitotic cyclins. Plants have multiple CDC20 gene copies whose functions have not been explored yet. In Arabidopsis thaliana there are five CDC20 isoforms and here we aimed at defining their contribution to cell cycle regulation, substrate selectivity and plant development.
Pubmed ID: 21687678 RIS Download
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Software environment and programming language for statistical computing and graphics. R is integrated suite of software facilities for data manipulation, calculation and graphical display. Can be extended via packages. Some packages are supplied with the R distribution and more are available through CRAN family.It compiles and runs on wide variety of UNIX platforms, Windows and MacOS.
View all literature mentionsA biology and bioinformatics laboratory at the Salk containing the following databases: SIGnAL T-DNA Express Arabidopsis Tiling Array Transcriptome Salk Insertion Sequence Database Arabidopsis Gene ORFeome Collection Salk Homozygote T-DNA Collection High Resolution Arabidopsis Methylome Perlegen Arabidopsis Resequencing Arabidopsis GMUCT Uncapped & Cleaved Transcripts Single Feature Polvmorphism Database High Resolution Arabidopsis Exosome Arabidopsis Interactome Single-base Resolution Epigenome Maps Transgenerational Inheritance of Methylation Variants Arabidopsis Cyclome Rice Functional Genomics Database Salk Arabidopsis 1,001 Genomes Arabidopsis Population Epigenomic Diversity Arabidopsis Biotic Stress Epigenome EIN3 -Ethylene Chip-seq/RNA-seq browser Soybean Epigenome Browser Human Human DNA Methylomes Human Pluripotent Cell Methylomes Human/Mouse Brain Methylomes Mouse Circadian Epigenome
View all literature mentionsA sweep-based data acquisition and analysis software package. Its uses range from a simple storage oscilloscope to complex applications requiring stimulus generation, data capture, control of external equipment and custom analysis. A built-in script language automates tasks and provides additional tools for custom analyses and applications. Signal includes functions for specific application areas, including dynamic clamp, whole cell and patch clamp electrophysiology, and evoked response including control of magnetic and other stimulus devices. Video tutorials and a demo version of Signal is available on the main page.
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