Preparing your results

Our searching services are busy right now. Your search will reload in five seconds.

X
Forgot Password

If you have forgotten your password you can enter your email here and get a temporary password sent to your email.

A user's guide to the encyclopedia of DNA elements (ENCODE).

PLoS biology | Apr 28, 2011

http://www.ncbi.nlm.nih.gov/pubmed/21526222

The mission of the Encyclopedia of DNA Elements (ENCODE) Project is to enable the scientific and medical communities to interpret the human genome sequence and apply it to understand human biology and improve health. The ENCODE Consortium is integrating multiple technologies and approaches in a collective effort to discover and define the functional elements encoded in the human genome, including genes, transcripts, and transcriptional regulatory regions, together with their attendant chromatin states and DNA methylation patterns. In the process, standards to ensure high-quality data have been implemented, and novel algorithms have been developed to facilitate analysis. Data and derived results are made available through a freely accessible database. Here we provide an overview of the project and the resources it is generating and illustrate the application of ENCODE data to interpret the human genome.

Pubmed ID: 21526222 RIS Download

Mesh terms: Base Sequence | Chromatin | Conserved Sequence | DNA Methylation | DNA-Binding Proteins | Databases, Nucleic Acid | Gene Components | Gene Expression Regulation | Genome, Human | Humans | Internet | Models, Genetic | Quality Control | RNA, Messenger | RNA-Binding Proteins

Research resources used in this publication

None found

Research tools detected in this publication

None found

Data used in this publication

None found

Associated grants

  • Agency: Wellcome Trust, Id: 095908
  • Agency: NIDDK NIH HHS, Id: R01 DK054369
  • Agency: NIDDK NIH HHS, Id: R01 DK065806
  • Agency: NHGRI NIH HHS, Id: R01 HG003143
  • Agency: NHGRI NIH HHS, Id: R01 HG004037
  • Agency: NHGRI NIH HHS, Id: RC2 HG005573

Mouse Genome Informatics (Data, Gene Annotation)

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.