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Copy number variations (CNVs) can contribute to variable degrees of fitness and/or disease predisposition. Recent studies show that at least 1% of any given genome is copy number variable when compared to the human reference sequence assembly. Homozygous deletions (or CNV nulls) that are found in the normal population are of particular interest because they may serve to define non-essential genes in human biology.
Pubmed ID: 21439084 RIS Download
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Cell line COS-7 is a Transformed cell line with a species of origin Chlorocebus aethiops (Green monkey)
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