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Galectin-1 is expressed in early-type neural progenitor cells and down-regulates neurogenesis in the adult hippocampus.

Molecular brain | 2011

In the adult mammalian brain, neural stem cells (NSCs) proliferate in the dentate gyrus (DG) of the hippocampus and generate new neurons throughout life. A multimodal protein, Galectin-1, is expressed in neural progenitor cells (NPCs) and implicated in the proliferation of the NPCs in the DG. However, little is known about its detailed expression profile in the NPCs and functions in adult neurogenesis in the DG.

Pubmed ID: 21269521 RIS Download

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C57BL/6J (tool)

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