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The Genomic HyperBrowser: inferential genomics at the sequence level.

Genome biology | Mar 2, 2010

http://www.ncbi.nlm.nih.gov/pubmed/21182759

The immense increase in the generation of genomic scale data poses an unmet analytical challenge, due to a lack of established methodology with the required flexibility and power. We propose a first principled approach to statistical analysis of sequence-level genomic information. We provide a growing collection of generic biological investigations that query pairwise relations between tracks, represented as mathematical objects, along the genome. The Genomic HyperBrowser implements the approach and is available at http://hyperbrowser.uio.no.

Pubmed ID: 21182759 RIS Download

Mesh terms: Base Pairing | Computational Biology | Exons | Gene Expression | Genome | Genomics | Histones | Models, Biological | Nucleic Acid Denaturation | Polymorphism, Single Nucleotide | Sequence Analysis | Software