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MicroRNAs both promote and antagonize longevity in C. elegans.

Current biology : CB | 2010

aging is under genetic control in C. elegans, but the mechanisms of life-span regulation are not completely known. MicroRNAs (miRNAs) regulate various aspects of development and metabolism, and one miRNA has been previously implicated in life span.

Pubmed ID: 21129974 RIS Download

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Associated grants

  • Agency: NIA NIH HHS, United States
    Id: R01 AG033921
  • Agency: NIA NIH HHS, United States
    Id: AG033921
  • Agency: NIA NIH HHS, United States
    Id: F32 AG030851
  • Agency: NIA NIH HHS, United States
    Id: 1F32AG030851
  • Agency: NIA NIH HHS, United States
    Id: R01 AG033921-08

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mirWIP (tool)

RRID:SCR_005055

Tool to search for targets of conserved microRNAs in Caenorhabditis elegans by weighting RISC-immunoprecipitation-enriched parameters.

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