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BigWig and BigBed: enabling browsing of large distributed datasets.

Bioinformatics (Oxford, England) | 2010

BigWig and BigBed files are compressed binary indexed files containing data at several resolutions that allow the high-performance display of next-generation sequencing experiment results in the UCSC Genome Browser. The visualization is implemented using a multi-layered software approach that takes advantage of specific capabilities of web-based protocols and Linux and UNIX operating systems files, R trees and various indexing and compression tricks. As a result, only the data needed to support the current browser view is transmitted rather than the entire file, enabling fast remote access to large distributed data sets.

Pubmed ID: 20639541 RIS Download

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Associated grants

  • Agency: NHGRI NIH HHS, United States
    Id: 5P41HG002371-09
  • Agency: Howard Hughes Medical Institute, United States
  • Agency: NHGRI NIH HHS, United States
    Id: P41 HG002371
  • Agency: NHGRI NIH HHS, United States
    Id: U41 HG004568
  • Agency: NHGRI NIH HHS, United States
    Id: 5U41HG004568-02

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Integrative Genomics Viewer (tool)

RRID:SCR_011793

A high-performance visualization tool for interactive exploration of large, integrated genomic datasets.

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