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Dramatic changes in gene expression occur in response to extracellular stimuli and during differentiation. Although transcriptional effects are important, alterations in mRNA decay also play a major role in achieving rapid and massive changes in mRNA abundance. Moreover, just as transcription factor activity varies between different cell types, the factors influencing mRNA decay are also cell-type specific.
Pubmed ID: 20574513 RIS Download
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Cell line C2C12 is a Spontaneously immortalized cell line with a species of origin Mus musculus (Mouse)
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