The serine/threonine kinase PIM1 has been implicated as an oncogene in various human cancers including lymphomas, gastric, colorectal and prostate carcinomas. In mouse models, Pim1 is known to cooperate with c-Myc to promote tumorigenicity. However, there has been limited analysis of the tumorigenic potential of Pim1 overexpression in benign and malignant human prostate cancer cells in vivo.
Pubmed ID: 20515470 RIS Download
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Cell line LNCaP is a Cancer cell line with a species of origin Homo sapiens (Human)
View all literature mentionsCell line DU145 is a Cancer cell line with a species of origin Homo sapiens (Human)
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