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The first decade of the National Drug Abuse Treatment Clinical Trials Network: bridging the gap between research and practice to improve drug abuse treatment.

The National Institute on Drug Abuse established the National Drug Abuse Treatment Clinical Trials Network (CTN) in 1999 to improve the quality of addiction treatment using science as the vehicle. The network brings providers from community-based drug abuse treatment programs and scientists from university-based research centers together in an alliance that fosters bidirectional communication and collaboration. Collaboration enhanced the relevance of research to practice and facilitated the development and implementation of evidence-based treatments in community practice settings. The CTN's 20 completed trials tested pharmacological, behavioral, and integrated treatment interventions for adolescents and adults; more than 11,000 individuals participated in the trials. This article reviews the rationale for the CTN, describes the translation of its guiding principles into research endeavors, and anticipates the future evolution of clinical research within the Network.

Pubmed ID: 20307794

Authors

  • Tai B
  • Straus MM
  • Liu D
  • Sparenborg S
  • Jackson R
  • McCarty D

Journal

Journal of substance abuse treatment

Publication Data

June 23, 2010

Associated Grants

  • Agency: NIDA NIH HHS, Id: U10 DA 13036
  • Agency: NIDA NIH HHS, Id: U10 DA 13714
  • Agency: NIDA NIH HHS, Id: U10 DA013036
  • Agency: NIDA NIH HHS, Id: U10 DA013036-09
  • Agency: NIDA NIH HHS, Id: U10 DA013714
  • Agency: NIDA NIH HHS, Id: U10 DA013714-09
  • Agency: Intramural NIH HHS, Id: Z99 DA999999

Mesh Terms

  • Adolescent
  • Adult
  • Clinical Trials as Topic
  • Cooperative Behavior
  • Evidence-Based Medicine
  • Humans
  • National Institute on Drug Abuse (U.S.)
  • Substance-Related Disorders
  • Translational Medical Research
  • United States