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The relationship between depression and smoking cessation outcomes in treatment-seeking substance abusers.

The National Drug Abuse Treatment Clinical Trials Network (CTN) recently completed a randomized, open label trial comparing treatment as usual (TAU) combined with nicotine patches plus cognitive behavioral group counseling for smoking cessation (n = 153) to TAU alone (n = 72) for patients enrolled in treatment programs for drug or alcohol dependence, who were interested in quitting smoking. This report is a secondary analysis evaluating the effect of depressive symptomatology (n = 70) or history of depression (n = 110) on smoking cessation outcomes. A significant association was seen between measures of depression and difficulty quitting cigarettes. Specifically, there was a greater probability for smoking abstinence for those with lower baseline Beck Depression Inventory II (BDI-II) scores. These data suggest that evaluation and treatment of depressive symptoms may play an important role in improving smoking cessation outcomes. (Am J Addict 2010;00:1-8).

Pubmed ID: 20163382 RIS Download

Mesh terms: Administration, Cutaneous | Adolescent | Adult | Behavior, Addictive | Cognitive Therapy | Combined Modality Therapy | Depressive Disorder, Major | Diagnosis, Dual (Psychiatry) | Female | Humans | Male | Nicotine | Patient Acceptance of Health Care | Psychotherapy, Group | Smoking Cessation | Substance-Related Disorders | Treatment Outcome

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Associated grants

  • Agency: NIDA NIH HHS, Id: U10 DA013046
  • Agency: NIDA NIH HHS, Id: U10 DA013035
  • Agency: NIDA NIH HHS, Id: U10 DA13727
  • Agency: NIDA NIH HHS, Id: U10 DA13046
  • Agency: NIDA NIH HHS, Id: U10 DA013727-08
  • Agency: NIDA NIH HHS, Id: U10 DA013035-07
  • Agency: NIDA NIH HHS, Id: U10 DA013727-10
  • Agency: NIDA NIH HHS, Id: K24 DA022412
  • Agency: NIDA NIH HHS, Id: U10 DA13035
  • Agency: NIDA NIH HHS, Id: U10 DA013727-09
  • Agency: NIDA NIH HHS, Id: U10 DA013727
  • Agency: NIDA NIH HHS, Id: U10 DA013046-09

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