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Characterization of Notch1 antibodies that inhibit signaling of both normal and mutated Notch1 receptors.

PloS one | 2010

Notch receptors normally play a key role in guiding a variety of cell fate decisions during development and differentiation of metazoan organisms. On the other hand, dysregulation of Notch1 signaling is associated with many different types of cancer as well as tumor angiogenesis, making Notch1 a potential therapeutic target.

Pubmed ID: 20161710 RIS Download

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

  • Agency: NCI NIH HHS, United States
    Id: R56 CA092433
  • Agency: NCI NIH HHS, United States
    Id: P01 CA119070-040003
  • Agency: NCI NIH HHS, United States
    Id: R56 CA092433-06A1
  • Agency: NCI NIH HHS, United States
    Id: R01 CA092433
  • Agency: NCI NIH HHS, United States
    Id: P01 CA119070-049001
  • Agency: PHS HHS, United States
    Id: P01 119070
  • Agency: NCI NIH HHS, United States
    Id: R01 CA092433-06A2
  • Agency: NCI NIH HHS, United States
    Id: P01 CA119070

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MxPro QPCR (tool)

RRID:SCR_016375

Software that performs data analysis algorithms for QPCR data. The software is included with the purchase of the Agilent MxPro QPCR System.

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